Deluise V P, Cobo L M, Chandler D
Ophthalmology. 1983 Jul;90(7):835-9. doi: 10.1016/s0161-6420(83)34478-x.
Corneal edema occurring in the congenital rubella syndrome can result from coexistent glaucoma or develop in the absence of an elevated intraocular pressure. We examined a 36-week-old female infant with documented congenital rubella syndrome who had bilateral corneal stromal edema without attendant congenital glaucoma. Histopathologic examination of the cornea revealed absent Descemet's membrane, deep interstitial keratitis, stromal corneal swelling, and deranged, focally absent endothelial cells. A viral infiltration of endothelium is postulated as the mechanism of the corneal edema and keratitis.
先天性风疹综合征中出现的角膜水肿可由并存的青光眼引起，也可在眼压不升高的情况下发生。我们检查了一名36周大的女婴，她患有先天性风疹综合征，双侧角膜基质水肿，但无先天性青光眼。角膜组织病理学检查显示Descemet膜缺失、深层间质性角膜炎、角膜基质肿胀以及内皮细胞排列紊乱、局部缺失。推测内皮细胞的病毒浸润是角膜水肿和角膜炎的发病机制。
