Damon G, Bourgeois J, Berthier J C, Denoyel G A, Fournier P, Bethenod M
Arch Fr Pediatr. 1983 Jun-Jul;40(6):491-3.
The authors report a case of neonatal herpes simplex infection with favourable outcome, without any sign of meningo-encephalitis or dissemination. The child was given antiviral treatment with Acyclovir from the first day of rash. Vesicle scraping and a complete serologic study of both child and mother proved infection was due to herpes simplex virus type I, transmitted to the neonate during primary maternal infection with gingivostomatitis beginning on the day of delivery. The different routes of postnatal contamination of the neonate by herpes virus and the risks of dissemination are reviewed. The importance of preventing contamination and dissemination of a known herpetic infection in maternity-hospitals and in nurseries for newborns is emphasized. Antiviral treatment should be used in all neonates with localized herpetic infection.
作者报告了一例新生儿单纯疱疹感染病例,预后良好,无任何脑膜脑炎或播散迹象。患儿自出疹首日起接受阿昔洛韦抗病毒治疗。对患儿及母亲进行的水疱刮片检查和全面血清学研究证明,感染是由I型单纯疱疹病毒引起的,该病毒在母亲分娩当日开始的原发性龈口炎感染期间传播给了新生儿。文中回顾了新生儿产后感染疱疹病毒的不同途径以及播散风险。强调了在妇产医院和新生儿保育室预防已知疱疹感染的污染和播散的重要性。所有患有局部疱疹感染的新生儿均应接受抗病毒治疗。