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[妊娠对未切除胸腺和切除胸腺大鼠止血系统状态的影响]

[Effect of pregnancy on the state of the hemostatic system in intact and thymectomized rats].

作者信息

Khyshova D R, Pisarevskaia L I, Makhakova G Ch, Kuznik B I, Tsybikov N N

出版信息

Biull Eksp Biol Med. 1983 Oct;96(10):26-8.

PMID:6684960
Abstract

Thymectomized rats developed hypercoagulation and inhibition of fibrinolysis. At the same time such animals showed a tendency towards a higher aggregation of platelets and enhanced antiaggregation activity of the vascular wall. Pregnant rats, both intact and thymectomized, exhibited hypocoagulation and inhibition of fibrinolysis. It is believed that the lack of differences in the hemostasis might be accounted for by activation of secretory function of the thymus in fetuses of pregnant thymectomized rats.

摘要

切除胸腺的大鼠出现高凝状态并伴有纤维蛋白溶解抑制。与此同时,这类动物表现出血小板聚集性增强以及血管壁抗聚集活性增强的趋势。完整的和切除胸腺的妊娠大鼠均表现出低凝状态和纤维蛋白溶解抑制。据信,妊娠并切除胸腺的大鼠胎儿胸腺分泌功能的激活可能是止血方面缺乏差异的原因。

相似文献

1
[Effect of pregnancy on the state of the hemostatic system in intact and thymectomized rats].[妊娠对未切除胸腺和切除胸腺大鼠止血系统状态的影响]
Biull Eksp Biol Med. 1983 Oct;96(10):26-8.
2
[Effect of thymalin and heterotransfusion on blood coagulation and fibrinolysis in thymectomized rats].[胸腺素与异种输血对去胸腺大鼠血液凝固及纤维蛋白溶解的影响]
Biull Eksp Biol Med. 1983 Feb;95(2):26-8.
3
[Effect of thymalin on thrombocyte aggregation and the antiaggregation activity of the vascular wall in intact and thymectomized rats].
Farmakol Toksikol. 1986 Mar-Apr;49(2):15-8.
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[Effect of histamine and thymarin on blood coagulation and fibrinolysis in intact and thymectomized rats].[组胺和胸腺素对完整及胸腺切除大鼠血液凝固和纤维蛋白溶解的影响]
Biull Eksp Biol Med. 1982 Sep;94(9):27-9.
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[Thrombocyte aggregation and the antiaggregation activity of the aorta in intact and thymectomized rats].[完整及胸腺切除大鼠的血小板聚集与主动脉抗聚集活性]
Patol Fiziol Eksp Ter. 1983 Jan-Feb(1):60-2.
6
[Effect of adrenaline and thymic factor on blood coagulation and fibrinolysis in healthy and thymectomized rats].[肾上腺素和胸腺因子对健康大鼠及胸腺切除大鼠血液凝固和纤维蛋白溶解的影响]
Biull Eksp Biol Med. 1981 Sep;92(9):264-6.
7
[Role of the thymus in regulating blood coagulation and fibrinolysis].[胸腺在调节血液凝固和纤维蛋白溶解中的作用]
Fiziol Zh SSSR Im I M Sechenova. 1982 Jan;68(1):52-8.
8
[Regulation of the fluid state of the blood in thymectomized rats following intravenous thrombin administration].
Biull Eksp Biol Med. 1981 Sep;92(9):285-7.
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[Effect of the thymic factor on blood coagulation and fibrinolysis in thymectomized rats].[胸腺因子对胸腺切除大鼠血液凝固和纤维蛋白溶解的影响]
Probl Endokrinol (Mosk). 1982 Jul-Aug;28(4):77-80.
10
[Morphological composition of the blood, the coagulating system and fibrinolysis in rats in the late period after thymectomy].[胸腺切除术后晚期大鼠的血液形态组成、凝血系统和纤维蛋白溶解]
Patol Fiziol Eksp Ter. 1984 Sep-Oct(5):62-4.