Kuznik B I, Tsybikov N N, Pisarevskaia L I, Morozov V G, Khavinson V Kh
Biull Eksp Biol Med. 1983 Feb;95(2):26-8.
Experiments on rats have shown that thymectomy brings about the development of hypercoagulation and inhibition of fibrinolysis. Heterotransfusion is accompanied by hypocoagulation and stimulation of fibrinolysis in both intact and thymectomized rats. At the same time fibrinolysis in thymectomized rats is stimulated to a lesser degree than in intact animals. Preinjection into thymectomized rats of the thymus low-molecular factor thymaline over one week does not only make blood coagulation and fibrinolysis return to normal but also leads to adequate changes in the hemostatic system in response to heterotransfusion.
对大鼠的实验表明，胸腺切除会导致高凝状态的发展和纤维蛋白溶解的抑制。在完整大鼠和胸腺切除大鼠中，异体输血均伴有低凝状态和纤维蛋白溶解的刺激。同时，胸腺切除大鼠的纤维蛋白溶解受到的刺激程度低于完整动物。在一周的时间里，向胸腺切除大鼠预先注射胸腺低分子因子胸腺素，不仅能使血液凝固和纤维蛋白溶解恢复正常，还能使止血系统对异体输血产生适当的变化。
