饲养条件对大鼠三项行为测试的影响。
Effects of housing conditions on three behavioral tests in rats.
作者信息
Xavier G F, Zelger K D, Zelger J L, de-Albuquerque A A
出版信息
Braz J Med Biol Res. 1983 Apr;16(1):65-71.
Groups of rats housed since weaning under two different kinds of housing conditions (wire and wooden cages) were compared at adulthood in the open field test, the step-through passive avoidance test, and for aggressiveness induced by REM-sleep deprivation and apomorphine administration. In the open field test wire-caged rats showed less rearing and grooming than wood-caged rats. This difference was accentuated by a single previous electrical shock (i.e., wire-caged rats exhibited less ambulation, rearing and grooming and more defecation than wood-caged rats, after shock) and was not altered by prior habituation to handling. In the passive avoidance test there were no significant differences between wire- and wood-caged rats. Wire-caged rats were more aggressive than wood-caged rats after REM-sleep deprivation and the administration of apomorphine. These results show that the control of previous housing conditions is an important variable to be considered in behavioral studies.
将自断奶起就饲养在两种不同饲养条件（铁丝笼和木笼）下的大鼠成年后进行比较，分别进行旷场试验、穿梭箱被动回避试验，以及通过剥夺快速眼动睡眠和注射阿扑吗啡诱导攻击行为的试验。在旷场试验中，铁丝笼饲养的大鼠与木笼饲养的大鼠相比，直立和理毛行为较少。单次电击会加剧这种差异（即电击后，铁丝笼饲养的大鼠比木笼饲养的大鼠活动、直立和理毛行为更少，排便更多），且先前的习惯化处理对其没有影响。在被动回避试验中，铁丝笼和木笼饲养的大鼠之间没有显著差异。在剥夺快速眼动睡眠并注射阿扑吗啡后，铁丝笼饲养的大鼠比木笼饲养的大鼠更具攻击性。这些结果表明，先前饲养条件的控制是行为研究中需要考虑的一个重要变量。
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