[Metabolic characteristics of a nystatin-resistant strain of a fungal producer of fusidic acid].
作者信息
Beliaeva T V, Bartoshevich Iu E, Zaslavskaia P L, Dmitrieva S V
出版信息
Antibiotiki. 1983 Dec;28(12):893-900.
PMID:6686428
Abstract
The physiological and morphofunctional properties of the polyene-sensitive and resistant mutants of fungus producing fusidic acid were studied comparatively. The highly active nystatin resistant mutant was characterized by the decreased growth rates, lowered sporulation levels, retarded synthesis of nucleic acids and protein, lower respiration activity and higher mycelium lipid contents. The ultrastructural investigation of the polyene-resistant strain revealed the presence of lower numbers of ribosomes, membrane structures and mitochondria. Destructive changes in mitochondria and lipid masses in the hyphal cytoplasm were also observed.
摘要
相似文献
1
[Metabolic characteristics of a nystatin-resistant strain of a fungal producer of fusidic acid].
Antibiotiki. 1983 Dec;28(12):893-900.
2
[Ultrastructure of the spores of fungal strains, producers of fusidic acid, varying in antibiotic activity].[不同抗生素活性的夫西地酸产生菌真菌菌株孢子的超微结构]
Antibiotiki. 1983 Aug;28(8):563-6.
3
[Morphofunctional characteristics of the development of strains of Fusidium coccineum differing in antibiotic activity in stab cultivation].
Mikrobiologiia. 1984 Mar-Apr;53(2):266-70.
4
[Some characteristics of fucidin biosynthesis].[梭链孢酸生物合成的一些特征]
Antibiotiki. 1975 Oct;20(10):867-71.
5
[Characteristics of fucidin biosynthesis by a Fusidium coccineum 257 A strain].[绯色梭链孢257 A菌株的梭链孢酸生物合成特性]
Antibiotiki. 1977 Jan;22(1):29-32.
6
[Degradation of cultural markers of Fusidium coccineum during the process of selection].[在筛选过程中红色梭链孢菌培养物标记物的降解]
Antibiotiki. 1973 Nov;18(11):981-6.
7
[Energy metabolism study of Fusidium coccineum strains with varying levels of antibiotic formation].[不同抗生素产生水平的绯红色梭链孢菌株的能量代谢研究]
Antibiotiki. 1978 Feb;23(2):109-14.
8
Comparison of the mutagenic effect of certain nitrosoamides on producers of antibiotics.某些亚硝基酰胺对抗生素产生菌的诱变效应比较。
Sov Genet. 1974 Mar 1;7(12):1566-72.
9
[Possible role of the respiratory system of Fusidium coccineum in regulating fusidic acid biosynthesis].[深红梭链孢呼吸系统在调节梭链孢酸生物合成中的可能作用]
Mikrobiologiia. 1980 Jul-Aug;49(4):493-500.
Zotero 插件