El-Labban N G, Lee K W
Histopathology. 1983 Nov;7(6):907-18. doi: 10.1111/j.1365-2559.1983.tb02305.x.
The ultrastructure of stromal mononuclear cells and giant cells were studied in two cases of central giant cell granuloma of the jaws. The majority of stromal cells superficially resembled fibroblasts, but also contained intracytoplasmic myofilaments with electron dense bodies similar to smooth muscle cells. These cells were referred to as myofibroblasts. The other type of mononuclear cells resembled macrophages. Many of the myofibroblast type cells appeared close to giant cells and signs of early fusion between them could be demonstrated. It is suggested from these results that the giant cells in central giant cell granuloma form and increase in size through fusion of these cells.
对两例颌骨中央巨细胞肉芽肿病例的基质单核细胞和巨细胞的超微结构进行了研究。大多数基质细胞表面上类似于成纤维细胞，但也含有胞质内肌丝以及与平滑肌细胞相似的电子致密体。这些细胞被称为肌成纤维细胞。另一类单核细胞类似于巨噬细胞。许多肌成纤维细胞样细胞靠近巨细胞，并且可以证明它们之间有早期融合的迹象。从这些结果推测，颌骨中央巨细胞肉芽肿中的巨细胞是通过这些细胞的融合形成并增大体积的。
