粉尘暴露激发试验作为衡量处理卵叶车前草产品时潜在致敏性和职业病风险的一种方法。

Dust exposure challenge test as a measure of potential allergenicity and occupational disease risk in handling of Ispaghula products.

作者信息

Machado L, Olsson G, Stålenheim G, Zetterström O

出版信息

Allergy. 1983 Feb;38(2):141-4. doi: 10.1111/j.1398-9995.1983.tb01598.x.

DOI:10.1111/j.1398-9995.1983.tb01598.x

Abstract

It is known that workers in the pharmaceutical industry, and nurses, can become sensitized and develop allergic respiratory symptoms by handling bulk laxatives containing Ispaghula powder. Fifteen individuals allergic to Ispaghula were challenged with a commercially available Ispaghula product and three other products manufactured in a way to make them less dusty. The results show that the use of products with smaller amounts of airborne particles results in a lower incidence of symptoms and thus probably reduces the potential occupational risk of sensitization to the Ispaghula allergen.

摘要

众所周知，制药行业的工人以及护士在处理含有卵叶车前子粉的散装泻药时，可能会产生过敏反应并出现过敏性呼吸道症状。15名对卵叶车前子过敏的个体分别接触了一种市售的卵叶车前子产品以及其他三种以减少扬尘方式生产的产品。结果表明，使用空气中颗粒含量较少的产品会降低症状发生率，因此可能会降低对卵叶车前子过敏原致敏的潜在职业风险。