Du Pasquier L, Wabl M R
Eur J Immunol. 1978 Jun;8(6):428-33. doi: 10.1002/eji.1830080611.
Anti-sheep red cell, anti-dinitrophenyl, anti-phosphorylcholine antibody responses have been followed in isogenic frogs of the genus Xenopus. Isoelectric focusing antibody patterns show a high degree of overlap for all antigens studied, and a heterogeneity that is lower than in mammals for the same antigens. Inheritance of antibody isoelectric focusing spectrotypes was demonstrated for sheep red cells and dinitrophenyl in two clones of isogenic animals. Outbred frogs show a higher frequency of spectrotype sharing than outbred mammals. It is therefore suggested that antibody diversity is lower in frogs than in mammals.
在非洲爪蟾属的同基因青蛙中追踪了抗绵羊红细胞、抗二硝基苯基、抗磷酰胆碱抗体反应。等电聚焦抗体模式显示，对于所有研究的抗原都有高度重叠，并且与相同抗原在哺乳动物中的情况相比，其异质性更低。在两个同基因动物克隆中，证明了绵羊红细胞和二硝基苯基的抗体等电聚焦光谱类型的遗传。远交青蛙显示出比远交哺乳动物更高的光谱类型共享频率。因此，有人提出青蛙中的抗体多样性低于哺乳动物。
