• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

晶状体蛋白的光解变化。

Photolytic changes in lens proteins.

作者信息

Dillon J

出版信息

Curr Eye Res. 1984 Jan;3(1):145-50. doi: 10.3109/02713688408997196.

DOI:10.3109/02713688408997196
PMID:6690217
Abstract

Many of the age related and cataractous changes that occur in the human lens may be due to some photolytic process. These include either the direct photolysis of lens protein or photosensitized reactions involving 3-OH Kyn glucoside. The extent to which these photochemical reactions play a role is determined by the level of lens oxygen and the presence of quenchers endogenous to the lens.

摘要

人类晶状体中发生的许多与年龄相关的和白内障性变化可能归因于某种光解过程。这些变化包括晶状体蛋白的直接光解或涉及3-羟基犬尿氨酸葡萄糖苷的光敏反应。这些光化学反应所起作用的程度由晶状体的氧含量水平以及晶状体中内源性淬灭剂的存在情况决定。

相似文献

1
Photolytic changes in lens proteins.晶状体蛋白的光解变化。
Curr Eye Res. 1984 Jan;3(1):145-50. doi: 10.3109/02713688408997196.
2
Minimization of photooxidative insult to calf lens protein irradiated with near UV-light in the presence of pigmented glucosides derived from human lens protein.在存在源自人晶状体蛋白的色素化糖苷的情况下,使小牛晶状体蛋白受近紫外光照射时的光氧化损伤最小化。
Exp Eye Res. 2004 Dec;79(6):833-7. doi: 10.1016/j.exer.2004.09.004.
3
The photolysis of lens fiber membranes.晶状体纤维细胞膜的光解作用。
Exp Eye Res. 1985 Jul;41(1):53-60. doi: 10.1016/0014-4835(85)90093-4.
4
Photochemistry of proteins: a review.蛋白质的光化学:综述
Curr Eye Res. 1984 Jan;3(1):137-44. doi: 10.3109/02713688408997195.
5
Tryptophan-derived ultraviolet filter compounds covalently bound to lens proteins are photosensitizers of oxidative damage.与晶状体蛋白共价结合的色氨酸衍生紫外线过滤化合物是氧化损伤的光敏剂。
Free Radic Biol Med. 2008 Mar 15;44(6):1108-19. doi: 10.1016/j.freeradbiomed.2007.12.003. Epub 2007 Dec 15.
6
Acceleration of calcium-induced aggregation of rat lens soluble protein by photosensitization with 8-methoxypsoralen and 3-hydroxy-L-kynurenine O-beta-glucoside.8-甲氧基补骨脂素和3-羟基-L-犬尿氨酸O-β-葡萄糖苷光致敏加速钙诱导的大鼠晶状体可溶性蛋白聚集
Exp Eye Res. 1982 Jun;34(6):953-60. doi: 10.1016/0014-4835(82)90075-6.
7
The photochemical attachment of the O-glucoside of 3-hydroxykynurenine to alpha-crystallin: a model for lenticular aging.3-羟基犬尿氨酸的O-葡萄糖苷与α-晶状体蛋白的光化学结合:晶状体老化的一个模型
Photochem Photobiol. 1999 Feb;69(2):248-53.
8
Calcium-induced lens protein aggregation accelerated by reactive oxygen species photosensitized in the presence of hydroxykynurenines.
Exp Eye Res. 1985 Jun;40(6):813-8. doi: 10.1016/0014-4835(85)90126-5.
9
3-Hydroxykynurenine bound to eye lens proteins induces oxidative modifications in crystalline proteins through a type I photosensitizing mechanism.3-羟基犬尿氨酸与眼睛晶状体蛋白结合,通过 I 型光敏化机制诱导晶状体蛋白发生氧化修饰。
Free Radic Biol Med. 2019 Sep;141:103-114. doi: 10.1016/j.freeradbiomed.2019.05.024. Epub 2019 May 22.
10
Cataracts and photochemical damage in the lens.
Ciba Found Symp. 1984;106:88-109. doi: 10.1002/9780470720875.ch6.

引用本文的文献

1
UV-B-induced damage to the lens in vitro: prevention by caffeine.紫外线B诱导的体外晶状体损伤:咖啡因的预防作用
J Ocul Pharmacol Ther. 2008 Oct;24(5):439-44. doi: 10.1089/jop.2008.0035.
2
The effect of single and repeated UVB radiation on rabbit lens.单次及重复紫外线B辐射对兔晶状体的影响。
Graefes Arch Clin Exp Ophthalmol. 2008 Apr;246(4):551-8. doi: 10.1007/s00417-007-0747-6. Epub 2008 Jan 12.
3
Ultraviolet radiation and the eye: an epidemiologic study.紫外线与眼睛:一项流行病学研究。
Trans Am Ophthalmol Soc. 1989;87:802-53.