Rundell K, Calenoff M, Renz C
J Virol. 1984 Jan;49(1):262-4. doi: 10.1128/JVI.49.1.262-264.1984.
Simian virus 40 small-t antigen allows the growth of CV-1 cells in concentrations of theophylline that normally prevent cell cycling. This effect is completely overcome by two ionophores that uncouple mitochondria and by the anti-mitochondrial drug methylglyoxal bis-(guanylhydrazone).
猿猴病毒40小t抗原能使CV-1细胞在通常会阻止细胞周期进程的茶碱浓度下生长。两种使线粒体解偶联的离子载体以及抗线粒体药物甲基乙二醛双(脒腙)能完全克服这种效应。