一种新的癌基因c-raf定位于小鼠6号染色体上。
A new oncogene, c-raf, is located on mouse chromosome 6.
作者信息
Kozak C, Gunnell M A, Rapp U R
出版信息
J Virol. 1984 Jan;49(1):297-9. doi: 10.1128/JVI.49.1.297-299.1984.
Abstract
The recently described acute transforming virus 3611-MSV contains cellular sequences designated v-raf. Mouse cellular DNA contains a single-copy sequence homologous to this oncogene (c-raf), and Southern blot analysis of hamster-mouse somatic cell hybrid DNAs showed that the mouse c-raf sequence is present on chromosome 6.
摘要
最近描述的急性转化病毒3611-MSV含有被命名为v-raf的细胞序列。小鼠细胞DNA含有一个与该癌基因（c-raf）同源的单拷贝序列，对仓鼠-小鼠体细胞杂交DNA进行的Southern印迹分析表明，小鼠c-raf序列存在于6号染色体上。
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