一种新的癌基因c-raf定位于小鼠6号染色体上。
A new oncogene, c-raf, is located on mouse chromosome 6.
作者信息
Kozak C, Gunnell M A, Rapp U R
出版信息
J Virol. 1984 Jan;49(1):297-9. doi: 10.1128/JVI.49.1.297-299.1984.
Abstract
The recently described acute transforming virus 3611-MSV contains cellular sequences designated v-raf. Mouse cellular DNA contains a single-copy sequence homologous to this oncogene (c-raf), and Southern blot analysis of hamster-mouse somatic cell hybrid DNAs showed that the mouse c-raf sequence is present on chromosome 6.
摘要
最近描述的急性转化病毒3611-MSV含有被命名为v-raf的细胞序列。小鼠细胞DNA含有一个与该癌基因（c-raf）同源的单拷贝序列，对仓鼠-小鼠体细胞杂交DNA进行的Southern印迹分析表明，小鼠c-raf序列存在于6号染色体上。
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本文引用的文献
1
Mouse c-myc oncogene is located on chromosome 15 and translocated to chromosome 12 in plasmacytomas.
Science. 1982 Dec 24;218(4579):1319-21. doi: 10.1126/science.7146913.
2
Chromosomal localization of the Moloney sarcoma virus mouse cellular (c-mos) sequence.
J Virol. 1982 Nov;44(2):752-4. doi: 10.1128/JVI.44.2.752-754.1982.
3
Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells.
Proc Natl Acad Sci U S A. 1982 Dec;79(24):7824-7. doi: 10.1073/pnas.79.24.7824.
4
A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia.
Nature. 1982 Dec 23;300(5894):765-7. doi: 10.1038/300765a0.
5
Genetic mapping of the ecotropic virus-inducing locus Akv-2 of the AKR mouse.
J Exp Med. 1980 Nov 1;152(5):1419-23. doi: 10.1084/jem.152.5.1419.
6
Genetic mapping of the mouse oncogenes c-Ha-ras-1 and c-fes to chromosome 7.
J Virol. 1983 Jul;47(1):217-20. doi: 10.1128/JVI.47.1.217-220.1983.
7
Human oncogene locations and chromosome aberrations.
Nature. 1983 Jan 27;301(5898):290-1. doi: 10.1038/301290a0.
8
Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells.
Proc Natl Acad Sci U S A. 1982 Dec;79(24):7837-41. doi: 10.1073/pnas.79.24.7837.
9
Specific chromosomal translocations and the genesis of B-cell-derived tumors in mice and men.
Cell. 1983 Feb;32(2):311-5. doi: 10.1016/0092-8674(83)90449-x.
10
Cellular oncogenes and retroviruses.
Annu Rev Biochem. 1983;52:301-54. doi: 10.1146/annurev.bi.52.070183.001505.
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