Chalew S A, McLaughlin J V, Mersey J H, Adams A J, Cornblath M, Kowarski A A
JAMA. 1984 Feb 3;251(5):612-5.
Patients with idiopathic postprandial syndrome (IPS) report recurrent postprandial episodes that resemble the clinical manifestations of hypoglycemia. In an effort to find objective criteria for diagnosis of IPS, we studied a group of patients with IPS and controls during an oral glucose tolerance test. Patients with IPS had a significantly lower mean glucose nadir and higher hypoglycemic index than controls. Although 74% of patients with IPS had glucose nadirs higher than 50 mg/dL, their responses of epinephrine, cortisol, growth hormone, glucagon, and norepinephrine were significantly higher than the respective changes in the controls. Of the five hormones, only the epinephrine response separated the patients from the controls without overlap. The epinephrine response may represent a valuable diagnostic criterion for this disorder.
特发性餐后综合征（IPS）患者报告反复出现餐后发作，类似于低血糖的临床表现。为了找到诊断IPS的客观标准，我们在口服葡萄糖耐量试验期间研究了一组IPS患者和对照组。IPS患者的平均血糖最低点显著低于对照组，低血糖指数更高。虽然74%的IPS患者血糖最低点高于50mg/dL，但其肾上腺素、皮质醇、生长激素、胰高血糖素和去甲肾上腺素的反应明显高于对照组的相应变化。在这五种激素中，只有肾上腺素反应能将患者与对照组区分开来，且无重叠。肾上腺素反应可能是这种疾病的一个有价值的诊断标准。
