Shannon H S, Hayes M, Julian J A, Muir D C
Br J Ind Med. 1984 Feb;41(1):35-8. doi: 10.1136/oem.41.1.35.
A historical prospective mortality study was conducted at an insulating wool plant in Ontario, Canada, on 2576 men who had worked for at least 90 days and were employed between 1955 and 1977. Eighty eight deaths were found in the 97.2% of men traced. Mortality was compared by the person-years method with that of the Ontario population. Measurements taken since 1977 show very low fibre concentrations. The overall standardised mortality ratio (SMR) was 78%, significantly below 100. Among plant only employees, seven deaths were attributed to lung cancer compared with 4.22 expected, a non-significant excess (SMR = 166; 95% confidence limits 67 to 342). No confirmed cases of mesothelioma were observed and no other disease was significantly increased in plant workers.
在加拿大安大略省的一家绝缘羊毛厂进行了一项历史性前瞻性死亡率研究,研究对象为1955年至1977年间工作至少90天的2576名男性。在追踪到的97.2%的男性中发现了88例死亡。采用人年法将死亡率与安大略省人口的死亡率进行了比较。自1977年以来的测量显示纤维浓度非常低。总体标准化死亡率(SMR)为78%,显著低于100。仅在工厂工作的员工中,有7例死亡归因于肺癌,而预期为4.22例,超出不显著(SMR = 166;95%置信区间为67至342)。未观察到确诊的间皮瘤病例,工厂工人中也没有其他疾病显著增加。