Shannon H S, Jamieson E, Julian J A, Muir D C
Occupational Health Program, McMaster University Health Sciences Centre, Hamilton, Ontario, Canada.
Br J Ind Med. 1990 Aug;47(8):533-6. doi: 10.1136/oem.47.8.533.
A historical prospective mortality study was conducted at a glass filament plant in Ontario, Canada. The cohort consisted of 1465 men and women who had worked for a total of at least one year between 1951 (when the operations began) and 1986. Ninety six deaths were found in the 96% of persons traced. Mortality was compared by the person-years method with that of the Ontario population. An estimate of cumulative dust exposure was made based on long term employees' recollections of past conditions. Overall mortality was below that expected (standardised mortality ratio (SMR) = 76) based on 82 deaths. There were 11 deaths due to lung cancer; slightly but not significantly more than expected (SMR = 136, p = 0.31). Analysis by both duration of employment and cumulative exposure showed this increase to be inconsistent with an occupational aetiology.
在加拿大安大略省的一家玻璃丝工厂进行了一项历史性前瞻性死亡率研究。该队列由1465名男性和女性组成,他们在1951年(工厂运营开始时)至1986年期间总共工作了至少一年。在追踪到的96%的人员中发现了96例死亡。采用人年法将死亡率与安大略省人口的死亡率进行比较。根据长期员工对过去情况的回忆,对累积粉尘暴露进行了估计。总体死亡率低于预期(标准化死亡率(SMR)=76),预期死亡82例。有11例死于肺癌;略高于预期但无显著差异(SMR=136,p=0.31)。按就业时长和累积暴露量进行的分析表明,这种增加与职业病因不一致。