Shuangshoti S, Benjavongkulchai S, Chittmittrapap S
J Surg Oncol. 1984 Feb;25(2):119-23. doi: 10.1002/jso.2930250214.
A malignant mesenchymoma consisting of nerve sheath sarcoma and liposarcoma occurred in the right median nerve of a 29-year-old man who did not have stigmata of von Recklinghausen neurofibromatosis. It produced pain at the affected part, referred pain to the palm, and weakness of muscles supplied by branches of this nerve. The tumor was first excised 1 month after its initial manifestation, but recurred twice and eventually metastasized to the lung within 19 months. It is suggested that aberrant differentiation of the mesenchymal component of the neural crest, the ectomesenchymal structure, has created this combined sarcoma of nerve sheath and liposarcoma, forming a malignant mesenchymoma.
一名29岁男性的右侧正中神经发生了由神经鞘肉瘤和脂肪肉瘤组成的恶性间叶瘤，该患者并无冯·雷克林豪森神经纤维瘤病的体征。肿瘤在受累部位引起疼痛，向手掌放射，并导致该神经分支所支配肌肉的无力。肿瘤在首次出现症状1个月后首次切除，但复发两次，最终在19个月内转移至肺部。提示神经嵴的间充质成分（外胚间充质结构）的异常分化产生了这种神经鞘和脂肪肉瘤的联合肉瘤，形成了恶性间叶瘤。
