生成核酸二级结构的非重叠展示。
Generating non-overlapping displays of nucleic acid secondary structure.
作者信息
Shapiro B A, Maizel J, Lipkin L E, Currey K, Whitney C
出版信息
Nucleic Acids Res. 1984 Jan 11;12(1 Pt 1):75-88. doi: 10.1093/nar/12.1part1.75.
Abstract
A new algorithm is presented which permits the display of nucleic acid secondary structure by computer. This algorithm circumvents the problem of overlapping portions of the molecule which is inherent in some other drawing programs. The results from this algorithm may also be used as input to the drawing algorithm previously reported in this journal [1] to untangle most of a drawing. The algorithm also represents the molecule in a form which makes visual comparisons for similarity quite easy since it guarantees that comparable features will reside in the same relative position in the drawings when the drawings are normalized.
摘要
本文提出了一种新算法，可通过计算机显示核酸二级结构。该算法避免了分子重叠部分的问题，而这在其他一些绘图程序中是固有的。该算法的结果也可作为输入，用于本刊之前报道的绘图算法[1]，以解开大部分绘图。该算法还以一种形式表示分子，使得相似性的视觉比较非常容易，因为它保证在绘图归一化时，可比较的特征将位于绘图中的相同相对位置。
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本文引用的文献
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2
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Nucleic Acids Res. 1982 Jan 11;10(1):403-19. doi: 10.1093/nar/10.1.403.
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Optimal computer folding of large RNA sequences using thermodynamics and auxiliary information.利用热力学和辅助信息对大型RNA序列进行最优计算机折叠
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6
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Proc Natl Acad Sci U S A. 1975 Jun;72(6):2017-21. doi: 10.1073/pnas.72.6.2017.
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