ten Kate L P, Boman H, Daiger S P, Motulsky A G
Am J Cardiol. 1984 Feb 1;53(4):399-403. doi: 10.1016/0002-9149(84)90001-8.
The frequency of myocardial infarction (MI) and coronary artery disease (CAD) was studied among the first-degree relatives of 126 spouses of male survivors of MI, and compared with the frequency of MI and CAD among relatives of 126 age-matched control subjects. MI and CAD were as frequent among the relatives of the wives as among the relatives of their husbands with MI. MI and CAD were less frequent among the relatives of control subjects. Familial aggregation of CAD, therefore, is not limited to patients' relatives, but also affects the wives' families. This finding can be explained by assortative mating, i.e., marriage partners choose mates with similar lifestyles and risk factors that lead to CAD.
对126名心肌梗死男性幸存者的配偶的一级亲属中心肌梗死（MI）和冠状动脉疾病（CAD）的发生频率进行了研究，并与126名年龄匹配的对照对象的亲属中MI和CAD的发生频率进行了比较。MI和CAD在心肌梗死男性患者妻子的亲属中的发生频率与在其丈夫亲属中的发生频率相同。MI和CAD在对照对象亲属中的发生频率较低。因此，CAD的家族聚集性不仅限于患者的亲属，还会影响其妻子的家族。这一发现可以用选型交配来解释，即婚姻伴侣会选择具有相似生活方式和导致CAD的危险因素的配偶。
