通过光化学二色性确定小牛胸腺染色质中核小体和连接DNA的取向
Orientation of nucleosomes and linker DNA in calf thymus chromatin determined by photochemical dichroism.
作者信息
Mitra S, Sen D, Crothers D M
出版信息
Nature. 1984;308(5956):247-50. doi: 10.1038/308247a0.
DOI:10.1038/308247a0
PMID:6700728
Abstract
The dichroism for photochemical attachment of a psoralen derivative to Mg2+-stabilized chromatin fibres is used to deduce the orientation of nucleosomal disks and linker DNA in the 30-nm fibre. The new technique of photochemical electric dichroism should have general applicability to problems of nucleic acid organization in cellular subunits and viruses.
摘要
补骨脂素衍生物与Mg2+稳定的染色质纤维进行光化学附着的二色性，被用于推断30纳米纤维中核小体盘和连接DNA的方向。光化学电二色性这项新技术应普遍适用于解决细胞亚基和病毒中核酸组织的问题。
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