Holzman G B, Ravitch M M, Metheny W, Rothert M L, Holmes M, Hoppe R B
Obstet Gynecol. 1984 Mar;63(3):303-11.
A study was undertaken to determine how physicians decide when to prescribe estrogen. Twenty-five gynecologists and 25 family physicians responded to case histories and a questionnaire regarding estrogen administration. There was no difference in mean probability of prescribing, 0.42 for gynecologists and 0.40 for family physicians. Endometrial cancer risk and vasomotor symptom severity were significant factors in prescribing judgments; osteoporosis risk and current treatment status were not. In linear regression analysis the constant, not factor weights, were significantly related to each physician's overall likelihood of prescribing and to the individual's self-characterization as prescriber or nonprescriber. Most physicians indicated that estrogen reduces fracture risk, and that progestin reduces cancer risk. Physicians' responses to cases were not consistent with these stated beliefs about estrogen effects.
一项研究旨在确定医生如何决定何时开雌激素处方。25名妇科医生和25名家庭医生对关于雌激素给药的病例史和问卷做出了回应。开处方的平均概率没有差异，妇科医生为0.42，家庭医生为0.40。子宫内膜癌风险和血管舒缩症状严重程度是开处方判断中的重要因素；骨质疏松症风险和当前治疗状况则不是。在线性回归分析中，常数而非因素权重与每位医生开处方的总体可能性以及个人将自己描述为开处方者或不开处方者显著相关。大多数医生表示，雌激素可降低骨折风险，而孕激素可降低癌症风险。医生对病例的反应与这些关于雌激素作用的既定信念不一致。
