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低出生体重儿中杜波维茨胎龄的不准确性。

Inaccuracy of Dubowitz gestational age in low birth weight infants.

作者信息

Spinnato J A, Sibai B M, Shaver D C, Anderson G D

出版信息

Obstet Gynecol. 1984 Apr;63(4):491-5.

PMID:6700894
Abstract

The Dubowitz gestational age was compared to the obstetric clinical age of 119 predominantly black mother-infant pairs for whom certain clinical criteria were met. Forty-five hypertensive and 74 nonhypertensive gestations with infant birth weight less than 2500 g were evaluated. Overall the clinical age was 33.6 +/- 4.5 weeks versus 34.7 +/- 4.3 weeks by Dubowitz age (P = NS). The Dubowitz age differed from clinical age by more than 2 weeks in 33.6% (40/119). Of gestations under 33 weeks (clinical age) (N = 45) the clinical age was 30.1 +/- 2.4 weeks as compared to the Dubowitz age of 32.2 +/- 2.7 weeks (P less than .01). Fifty-one percent (23/45) of Dubowitz ages were more than two weeks discordant with the clinical age. The Dubowitz assessment of gestational age may be unacceptably inaccurate in the determination of gestational age in low birth weight infants, particularly in those whose gestational age is less than 33 weeks. The findings suggest that studies in which conclusions were based on the Dubowitz age assessment may need reevaluation.

摘要

将119对主要为黑人的母婴对(满足特定临床标准)的杜波维茨胎龄与产科临床胎龄进行了比较。对45例高血压妊娠和74例非高血压妊娠且婴儿出生体重小于2500g的情况进行了评估。总体而言,临床胎龄为33.6±4.5周,而杜波维茨胎龄为34.7±4.3周(P=无显著差异)。杜波维茨胎龄与临床胎龄相差超过2周的情况占33.6%(40/119)。在临床胎龄小于33周的妊娠中(N=45),临床胎龄为30.1±2.4周,而杜波维茨胎龄为32.2±2.7周(P<0.01)。51%(23/45)的杜波维茨胎龄与临床胎龄相差超过两周。在确定低出生体重婴儿的胎龄时,杜波维茨胎龄评估可能不准确到令人无法接受的程度,尤其是对于那些胎龄小于33周的婴儿。研究结果表明,那些基于杜波维茨胎龄评估得出结论的研究可能需要重新评估。

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