McCormick D A, Thompson R F
Science. 1984 Jan 20;223(4633):296-9. doi: 10.1126/science.6701513.
Classical conditioning of the eyelid response in the rabbit was used to investigate the neuronal structures mediating basic associative learning of discrete, adaptive responses. Lesions of the ipsilateral dentate-interpositus nuclei, but not of the cerebellar cortex, abolished the learned eyeblink response. Recordings from these nuclei have revealed neuronal responses related to the learning of the response. Stimulating these recording sites produced the eyelid response. The dentate-interpositus nuclei were concluded to be critically involved in the learning and production of classically conditioned responses.
通过对家兔眼睑反应进行经典条件反射来研究介导离散适应性反应基本联想学习的神经元结构。同侧齿状核-间位核受损而非小脑皮质受损会消除习得的眨眼反应。对这些核的记录揭示了与反应学习相关的神经元反应。刺激这些记录部位会产生眼睑反应。由此得出结论，齿状核-间位核在经典条件反射反应的学习和产生过程中起着关键作用。
