小鼠睾丸α-微管蛋白基因的单倍体表达
Haploid expression of a mouse testis alpha-tubulin gene.
作者信息
Distel R J, Kleene K C, Hecht N B
出版信息
Science. 1984 Apr 6;224(4644):68-70. doi: 10.1126/science.6701535.
PMID:6701535
Abstract
A complementary DNA clone for an alpha-tubulin has been isolated from a mouse testis complementary DNA library. The untranslated 3' end of this complementary DNA is homologous to two RNA transcripts present in postmeiotic cells of the testis but absent from meiotic cells and from several tissues including brain. The temporal expression of this alpha-tubulin complementary DNA provides evidence for the haploid expression of a mammalian structural gene.
摘要
已从小鼠睾丸互补DNA文库中分离出一个α-微管蛋白的互补DNA克隆。该互补DNA的非翻译3'端与睾丸减数分裂后细胞中存在的两种RNA转录本同源，但在减数分裂细胞和包括脑在内的几种组织中不存在。这种α-微管蛋白互补DNA的时间表达为哺乳动物结构基因的单倍体表达提供了证据。
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