Langevin J M, Nivatvongs S
Am J Surg. 1984 Mar;147(3):330-3. doi: 10.1016/0002-9610(84)90161-2.
The reported incidence of synchronous primary cancers and polyps associated with single cancers of the large bowel is varied. In a prospective study over a 5 year period, 166 patients with primary colorectal cancer had either total colonoscopy preoperatively or total colonoscopy within 6 months of surgical resection. One hundred seventy-eight cancers were detected. Synchronous cancers were found in eight patients (5 percent), and benign neoplastic polyps were demonstrated in 46 patients with single cancers (28 percent) and in 112 patients with synchronous primary cancers (38 percent). Of significance is that seven of eight (88 percent) synchronous cancers would not have been included in the standard resection for the index primary cancer. Similarly 31 of 46 neoplastic polyps (67 percent) were not in the same surgical segment as the primary cancer. Total large bowel evaluation, preferably using colonoscopy, is essential in all patients with cancer of the large bowel.
据报道，与大肠单一癌症相关的同步原发性癌症和息肉的发病率各不相同。在一项为期5年的前瞻性研究中，166例原发性结直肠癌患者在术前或手术切除后6个月内接受了全结肠镜检查。共检测到178处癌症。8例患者（5%）发现了同步癌症，46例单一癌症患者（28%）和112例同步原发性癌症患者（38%）发现了良性肿瘤性息肉。值得注意的是，8例同步癌症中的7例（88%）不会被纳入索引原发性癌症的标准切除范围内。同样，46例肿瘤性息肉中的31例（67%）与原发性癌症不在同一手术节段。对所有大肠癌患者进行全大肠评估，最好采用结肠镜检查，这是至关重要的。
