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替莫西林与其他β-内酰胺类抗生素联合使用的效果。

Effect of temocillin in combination with other beta-lactam antibiotics.

作者信息

Verbist L, Verhaegen J

出版信息

Antimicrob Agents Chemother. 1984 Jan;25(1):142-4. doi: 10.1128/AAC.25.1.142.

Abstract

The antibacterial interactions of temocillin with other beta-lactams were tested by checkerboard combination in Mueller-Hinton agar against 146 strains of members of the family Enterobacteriaceae, 35 Pseudomonas aeruginosa strains, and 35 Staphylococcus aureus strains. Most combinations showed a moderate degree of synergism. In only one Klebsiella strain was minor antagonism observed between temocillin and ampicillin.

摘要

通过棋盘格组合法,在穆勒-欣顿琼脂培养基上测试了替莫西林与其他β-内酰胺类药物对146株肠杆菌科细菌、35株铜绿假单胞菌和35株金黄色葡萄球菌的抗菌相互作用。大多数组合显示出中等程度的协同作用。仅在一株克雷伯菌中观察到替莫西林与氨苄西林之间存在轻微拮抗作用。

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