替莫西林（BRL 17421）的体外活性，一种新型的β-内酰胺酶稳定青霉素。
In vitro activity of temocillin (BRL 17421), a novel beta-lactamase-stable penicillin.
作者信息
Verbist L
出版信息
Antimicrob Agents Chemother. 1982 Jul;22(1):157-61. doi: 10.1128/AAC.22.1.157.
Abstract
The new in vitro activity of temocillin (BRL 17421), a new beta-lactamase-stable penicillin, was compared with those of other beta-lactam antibiotics for over 500 clinical bacterial isolates. Temocillin inhibited 94% of the Enterobacteriaceae organisms at concentrations of 0.5 to 8 microgram/ml, regardless of organisms resistance to ampicillin, ticarcillin, cefazolin, or combinations thereof. Most pseudomonas aeruginosa isolates and all staphylococci and streptococci tested were resistant to temocillin.
摘要
新型β-内酰胺酶稳定青霉素替莫西林（BRL 17421）的体外新活性与其他β-内酰胺类抗生素针对500多株临床分离细菌进行了比较。替莫西林在浓度为0.5至8微克/毫升时可抑制94%的肠杆菌科细菌，无论这些细菌对氨苄西林、替卡西林、头孢唑林或其组合是否耐药。大多数铜绿假单胞菌分离株以及所有测试的葡萄球菌和链球菌对替莫西林耐药。
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本文引用的文献
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GR-20263: a new aminothiazolyl cephalosporin with high activity against Pseudomonas and Enterobacteriaceae.GR - 20263：一种对假单胞菌属和肠杆菌科具有高活性的新型氨基噻唑基头孢菌素。
Antimicrob Agents Chemother. 1980 May;17(5):807-12. doi: 10.1128/AAC.17.5.807.
2
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Antimicrob Agents Chemother. 1981 Jul;20(1):38-46. doi: 10.1128/AAC.20.1.38.
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