• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

将全血与1,6-二磷酸果糖一起孵育后,红细胞内1,6-二磷酸果糖增加。

Increase of intraerythrocytic fructose-1,6-diphosphate after incubation of whole human blood with fructose-1,6-diphosphate.

作者信息

Lazzarino G, Cattani L, Costrini R, Mulieri L, Candiani A, Galzigna L

出版信息

Clin Biochem. 1984 Feb;17(1):42-5. doi: 10.1016/s0009-9120(84)90480-6.

DOI:10.1016/s0009-9120(84)90480-6
PMID:6705189
Abstract

The incubation of whole blood with fructose-1,6-diphosphate (FDP) entails a statistically significant increase of intraerythrocytic FDP together with a decrease of blood glucose. The increase is not significant when equimolar amounts of fructose plus twice molar phosphate are used. The effect of FDP is decreased in the presence of an excess of oxygen. FDP added to the whole blood is removed from plasma by the activity of plasma enzymes and by the presence of blood cells as well. No specific interaction of FDP with plasma proteins seems to occur and the effects of FDP addition last longer than is compatible with the presence of FDP in the plasma.

摘要

全血与1,6 - 二磷酸果糖(FDP)温育会使红细胞内FDP在统计学上显著增加,同时血糖降低。当使用等摩尔量的果糖加两倍摩尔量的磷酸盐时,这种增加并不显著。在氧气过量的情况下,FDP的作用会减弱。添加到全血中的FDP会通过血浆酶的活性以及血细胞的存在从血浆中被清除。FDP与血浆蛋白似乎没有特异性相互作用,并且添加FDP的效果持续时间比血浆中FDP的存在时间更长。

相似文献

1
Increase of intraerythrocytic fructose-1,6-diphosphate after incubation of whole human blood with fructose-1,6-diphosphate.将全血与1,6-二磷酸果糖一起孵育后,红细胞内1,6-二磷酸果糖增加。
Clin Biochem. 1984 Feb;17(1):42-5. doi: 10.1016/s0009-9120(84)90480-6.
2
Plasma and erythrocyte concentrations of fructose-1,6-diphosphate after intravenous administration in humans.人体静脉注射后血浆和红细胞中1,6 - 二磷酸果糖的浓度。
Farmaco Prat. 1984 Feb;39(2):33-7.
3
Fructose 2,6-bisphosphate and glucose 1,6-bisphosphate in erythrocytes during chicken development.
FEBS Lett. 1986 Dec 15;209(2):254-6. doi: 10.1016/0014-5793(86)81122-x.
4
Fructose 2,6-bisphosphate in rat erythrocytes. Inhibition of fructose 2,6-bisphosphate synthesis and measurement by glycerate 2,3-bisphosphate.大鼠红细胞中的果糖-2,6-二磷酸。甘油酸-2,3-二磷酸对果糖-2,6-二磷酸合成的抑制作用及测定
Biochem J. 1987 May 15;244(1):235-8. doi: 10.1042/bj2440235.
5
Fructose 2,6-bisphosphate in human platelets: its possible role in the control of basal and thrombin-stimulated glycolysis.
Biochem Biophys Res Commun. 1986 Jul 31;138(2):666-72. doi: 10.1016/s0006-291x(86)80548-4.
6
First results obtained with fructose-1, 6-diphosphate (FDP) in the "hyperinsulinaemia" (excessive insulin release).在“高胰岛素血症”(胰岛素过度释放)中使用1,6-二磷酸果糖(FDP)获得的初步结果。
Pharmacol Res Commun. 1979 Feb;11(2):121-32. doi: 10.1016/s0031-6989(79)80066-1.
7
Fructose 2,6-bisphosphate and glucose 1,6-bisphosphate in avian and mammalian erythroid cells.
Biomed Biochim Acta. 1987;46(2-3):S258-62.
8
Fructose 2,6-bisphosphate and glucose 1,6-bisphosphate levels in erythrocytes with high and low 2,3-bisphosphoglycerate content during postnatal development.出生后发育过程中2,3-二磷酸甘油酸含量高和低的红细胞中果糖2,6-二磷酸和葡萄糖1,6-二磷酸的水平
FEBS Lett. 1989 Jul 17;251(1-2):74-8. doi: 10.1016/0014-5793(89)81431-0.
9
Fructose 2,6-bisphosphate in human erythrocytes.人红细胞中的果糖-2,6-二磷酸
J Biochem. 1988 Jun;103(6):903-4. doi: 10.1093/oxfordjournals.jbchem.a122384.
10
Enzymatic pattern of glucose metabolic pathways in pyruvate kinase-deficient erythrocytes.丙酮酸激酶缺乏的红细胞中葡萄糖代谢途径的酶模式。
Clin Chim Acta. 1975 Oct 15;64(2):165-72. doi: 10.1016/0009-8981(75)90198-9.

引用本文的文献

1
Glucose limitation activates AMPK coupled SENP1-Sirt3 signalling in mitochondria for T cell memory development.葡萄糖限制激活 AMPK 偶联 SENP1-Sirt3 信号通路在 T 细胞记忆发育中的作用。
Nat Commun. 2021 Jul 16;12(1):4371. doi: 10.1038/s41467-021-24619-2.
2
Fructose-1,6-Bisphosphate Protects Hippocampal Rat Slices from NMDA Excitotoxicity.1,6-二磷酸果糖保护海马脑片免受 NMDA 兴奋性毒性。
Int J Mol Sci. 2019 May 7;20(9):2239. doi: 10.3390/ijms20092239.
3
Characterization of the high-affinity uptake of fructose-1,6-bisphosphate by cardiac myocytes.
心肌细胞对果糖-1,6-二磷酸高亲和力摄取的特性。
Mol Cell Biochem. 2012 Jul;366(1-2):31-9. doi: 10.1007/s11010-012-1279-x. Epub 2012 Mar 18.
4
Permeability of fructose-1,6-bisphosphate in liposomes and cardiac myocytes.果糖-1,6-二磷酸在脂质体和心肌细胞中的通透性。
Mol Cell Biochem. 2004 Apr;259(1-2):105-14. doi: 10.1023/b:mcbi.0000021356.89867.0d.
5
Fructose-1,6-bisphosphate as a metabolic substrate in hog ileum smooth muscle during hypoxia.果糖-1,6-二磷酸在缺氧时作为猪回肠平滑肌的代谢底物。
Mol Cell Biochem. 1996 Jan 12;154(1):83-93. doi: 10.1007/BF00248465.
6
Energy metabolism in hypoxic astrocytes: protective mechanism of fructose-1,6-bisphosphate.缺氧星形胶质细胞中的能量代谢:1,6-二磷酸果糖的保护机制
Neurochem Res. 1995 Jul;20(7):785-92. doi: 10.1007/BF00969690.
7
Proton and potassium fluxes in rat red blood cells incubated with sugar phosphates.与磷酸糖一起孵育的大鼠红细胞中的质子和钾离子通量
Experientia. 1986 Feb 15;42(2):138-9. doi: 10.1007/BF01952434.
8
Developmental cardiac metabolism in health and disease.健康与疾病状态下的心脏发育代谢
Pediatr Cardiol. 1989 Summer;10(3):150-8. doi: 10.1007/BF02081679.
9
Fructose-1,6-diphosphate counteracts ethanol-stimulated calcium uptake in isolated BHK cells.果糖-1,6-二磷酸可对抗乙醇刺激的离体BHK细胞对钙的摄取。
Mol Cell Biochem. 1990 Jun 1;95(1):89-93. doi: 10.1007/BF00219534.