Vitali T, Impicciatore M, Plazzi P V, Bordi F, Vitto M
Farmaco Sci. 1984 Jan;39(1):70-80.
The syntheses of 2-(2-amino-4-imidazolyl)ethylamine (2-aminohistamine) dihydrochloride and of the corresponding 5-methyl derivative are described. The histamine-like properties of the two salts are tested in vitro on isolated ileum and gastric fundus of guinea-pig. The results are discussed and compared with those of other H2-agonists.
描述了2-(2-氨基-4-咪唑基)乙胺(2-氨基组胺)二盐酸盐及其相应的5-甲基衍生物的合成。在豚鼠离体回肠和胃底上对这两种盐的组胺样性质进行了体外测试。对结果进行了讨论,并与其他H2激动剂的结果进行了比较。