老年疗养院患者的血清地高辛水平：常规定期测量的评估

Serum digoxin levels in elderly nursing home patients: appraisal of routine periodic measurements.

作者信息

Dimant J, Merrit W

出版信息

J Am Geriatr Soc. 1978 Aug;26(8):378-9. doi: 10.1111/j.1532-5415.1978.tb03689.x.

DOI:10.1111/j.1532-5415.1978.tb03689.x

Abstract

An assessment was made of the clinical value of routine periodic measurement of serum digoxin levels in 51 elderly nursing home patients with cardiac disease. The findings showed that the serum digoxin level was not correlated with the dosage of digoxin nor the patient's clinical state of digitalization. All patients were effectively digitalized, as judged clinically, and no digitalis toxicity occurred despite a wide range of serum digoxin levels. When adequate medical supervision, electrocardiograms, roentgenograms, serum electrolyte determinations and renal function tests are available, the routine periodic measurement of serum digoxin concentration does not offer any additional benefit in the management of nursing home patients with cardiac disease.

摘要

对51名患有心脏病的老年疗养院患者定期进行血清地高辛水平常规测量的临床价值进行了评估。结果显示，血清地高辛水平与地高辛剂量以及患者的洋地黄化临床状态均无相关性。从临床判断，所有患者均实现了有效的洋地黄化，尽管血清地高辛水平范围很广，但未发生洋地黄中毒。当有足够的医疗监督、心电图、X线片、血清电解质测定和肾功能检查时，对患有心脏病的疗养院患者进行血清地高辛浓度的常规定期测量在管理中并无任何额外益处。