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[女性良性对称性脂肪瘤病。与酒精性肝病的关联]

[Benign symmetrical lipomatosis in women. Association with alcoholic hepatopathy].

作者信息

Kölble K, Veltman G

出版信息

Hautarzt. 1984 Jan;35(1):33-8.

PMID:6706573
Abstract

Benign symmetric lipomatosis or Launois-Bensaude syndrome is a condition characterized by diffuse, unencapsulated, painless growth of lipomatous tissue with a peculiar symmetric topology occurring predominantly in middle-aged men. In the present study a short survey of the clinical manifestations, differential diagnosis, current pathophysiologic theories, and therapy of this disease is given. From the literature published since 1950 112 observations are reviewed with respect to alcohol abuse in the premorbid period and other coexisting illnesses. Of the patients 70% were heavy drinkers and in over 45% significant liver damage was present. In addition, two rare cases of benign symmetric lipomatosis in women, aged 42 and 49 years, respectively, are presented. Both were alcoholics with hepatic sequelae. The possible existence of a female morphological subtype of benign symmetric lipomatosis is ventilated and its identity with Touraine-Renault's segmental lipomatosis of the trunk suspected.

摘要

良性对称性脂肪瘤病或洛努瓦-本索德综合征是一种以脂肪组织弥漫性、无包膜、无痛性生长为特征的疾病,具有特殊的对称形态,主要发生于中年男性。本研究对该疾病的临床表现、鉴别诊断、当前病理生理理论及治疗进行了简要综述。对1950年以来发表的文献中112例观察病例进行了病前酗酒情况及其他并存疾病方面的回顾。患者中70%为重度饮酒者,超过45%存在明显肝损害。此外,还报告了两例分别为42岁和49岁女性的罕见良性对称性脂肪瘤病病例。两人均为酗酒者且有肝脏后遗症。文中探讨了良性对称性脂肪瘤病女性形态学亚型可能存在的情况,并怀疑其与图赖讷-雷诺躯干节段性脂肪瘤病相同。

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