多发性硬化症患者脑脊液和血清中缺乏寡克隆IgA 。
Absence of oligoclonal IgA in CSF and serum of multiple sclerosis patients.
作者信息
Mehta P D, Patrick B A, Miller J A
出版信息
J Neuroimmunol. 1984 Feb;6(1):67-9. doi: 10.1016/0165-5728(84)90044-4.
PMID:6707196
Abstract
CSF and serum from patients with MS and other neurologic diseases were analyzed by isoelectric focusing (IEF) in polyacrylamide gel and immunofixation with specific anti human IgA sera. The IgA band patterns seen in pH 4.5-6.0 region were rather diffuse and lacked oligoclonal feature.
摘要
采用聚丙烯酰胺凝胶等电聚焦（IEF）和特异性抗人IgA血清免疫固定法，对多发性硬化症（MS）患者及其他神经疾病患者的脑脊液（CSF）和血清进行分析。在pH 4.5 - 6.0区域观察到的IgA条带模式较为弥散，缺乏寡克隆特征。
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