Rollason T P, Stone J, Rhodes J M
J Clin Pathol. 1984 Jan;37(1):23-6. doi: 10.1136/jcp.37.1.23.
A retrospective light microscopic study of 310 consecutive endoscopic gastric biopsy specimens was performed. Spiral bacteria were found in 42% of cases and, apart from occasional organisms in parietal cell canaliculi, were confined to the surface of the glands and epithelium. Electron microscopic study of selected cases showed the bacteria to be approximately 6 micron maximum length and 0.7 micron diameter with a spiral periodicity of 1.2 micron. A significant association between the occurrence of spiral bacteria and gastritis was noted but not with carcinoma, peptic ulceration, or high pH of the gastric aspirate.
对310例连续的内镜下胃活检标本进行了回顾性光学显微镜研究。42%的病例中发现了螺旋菌，除了壁细胞小管中偶尔出现的微生物外，螺旋菌局限于腺表面和上皮。对选定病例的电子显微镜研究显示，这些细菌最长约6微米，直径0.7微米，螺旋周期为1.2微米。注意到螺旋菌的出现与胃炎之间存在显著关联，但与癌症、消化性溃疡或胃吸出物的高pH值无关。
