Watkins W B, Moore L G, Flint A P, Sheldrick E L
Peptides. 1984 Jan-Feb;5(1):61-4. doi: 10.1016/0196-9781(84)90052-4.
Measurements of venoarterial concentration differences across the ovary in anesthetized sheep have demonstrated that the ovary secretes ovine neurophysin I/II (oNP I/II) and that this process is stimulated by the prostaglandin F2 alpha analogue, cloprostenol. A parallel increase in the secretion of oxytocin (OT) was observed in response to cloprostenol, and the mean molar ratio of oNP I/II to OT secreted was 1.2. There was no detectable ovarian secretion of oNP III. Secretion of oNP I/II and OT was absent after hysterectomy. The data support other evidence indicating that the corpus luteum synthesizes OT, and confirm that the neurophysin associated with OT in the sheep is oNP I/II.
对麻醉绵羊卵巢动静脉浓度差的测量表明，卵巢分泌羊神经垂体素I/II（oNP I/II），且该过程受到前列腺素F2α类似物氯前列醇的刺激。观察到氯前列醇作用下催产素（OT）分泌平行增加，分泌的oNP I/II与OT的平均摩尔比为1.2。未检测到卵巢分泌oNP III。子宫切除术后oNP I/II和OT分泌消失。这些数据支持了其他表明黄体合成OT的证据，并证实绵羊中与OT相关的神经垂体素是oNP I/II。
