巴氯芬撤药后一名患者出现的运动障碍和精神病
Dyskinesia and psychosis in a patient following baclofen withdrawal.
作者信息
Kirubakaran V, Mayfield D, Rengachary S
出版信息
Am J Psychiatry. 1984 May;141(5):692-3. doi: 10.1176/ajp.141.5.692.
PMID:6711693
Abstract
A paraplegic man with no history of psychiatric illness developed psychosis and dyskinesia following abrupt withdrawal of baclofen; the symptoms resolved 72 hours after resumption of the drug. The psychosis and dyskinesia may have been a manifestation of baclofen's alteration of cerebral dopaminergic mechanisms.
摘要
一名无精神疾病史的截瘫男子在突然停用巴氯芬后出现精神病和运动障碍；恢复用药72小时后症状缓解。精神病和运动障碍可能是巴氯芬改变脑多巴胺能机制的一种表现。
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