强直性脊柱炎患者直肠固有层中含IgG细胞数量增加。
Increased numbers of IgG-containing cells in rectal lamina propria of patients with ankylosing spondylitis.
作者信息
Stodell M A, Butler R C, Zemelman V A, Henry K, Brewerton D A
出版信息
Ann Rheum Dis. 1984 Apr;43(2):172-6. doi: 10.1136/ard.43.2.172.
Abstract
Using an indirect immunoperoxidase technique we found the numbers of IgG-containing cells in the rectal lamina propria to be increased in patients with ankylosing spondylitis compared with controls, but not in patients with acute anterior uveitis or rheumatoid arthritis, or in the first-degree relatives of patients with ankylosing spondylitis. No differences between diagnostic groups were detected in the numbers of cells containing IgA, IgM, IgD, or IgE. The total numbers of plasma cells in the rectal lamina propria were not significantly increased. Similar increases of IgG-containing cells were not found in the duodenal lamina propria of patients with ankylosing spondylitis.
摘要
采用间接免疫过氧化物酶技术，我们发现，与对照组相比，强直性脊柱炎患者直肠固有层中含IgG的细胞数量增加，但急性前葡萄膜炎或类风湿关节炎患者以及强直性脊柱炎患者的一级亲属中未出现这种情况。在含IgA、IgM、IgD或IgE的细胞数量方面，各诊断组之间未检测到差异。直肠固有层中浆细胞的总数没有显著增加。在强直性脊柱炎患者的十二指肠固有层中未发现含IgG细胞的类似增加情况。
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