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风湿性多肌痛与抗线粒体抗体

Polymyalgia rheumatica and antimitochondrial antibodies.

作者信息

Sattar M A, Cawley M I, Hamblin T J, Robertson J C

出版信息

Ann Rheum Dis. 1984 Apr;43(2):264-6. doi: 10.1136/ard.43.2.264.

Abstract

Antimitochondrial antibodies (AMA) were detected in the sera of 11 of 36 patients with a clinical diagnosis of polymyalgia rheumatica (PMR) in whom comprehensive autoantibody screening had been performed. AMA did not correlate with biochemical changes of hepatic dysfunction, which are common in PMR, nor with parameters of musculoskeletal inflammation. Possible explanations are discussed.

摘要

在36例临床诊断为风湿性多肌痛(PMR)且已进行全面自身抗体筛查的患者中,11例患者血清中检测到抗线粒体抗体(AMA)。AMA与PMR中常见的肝功能障碍生化变化无关,也与肌肉骨骼炎症参数无关。文中讨论了可能的解释。

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本文引用的文献

3
Ultrastructural examination of the skeletal muscles in polymyalgia rheumatica.
J Pathol. 1982 Jul;137(3):181-92. doi: 10.1002/path.1711370303.
7
Giant-cell arteritis and raised serum-alkaline-phosphatase levels.
Lancet. 1972 Jul 1;2(7766):48. doi: 10.1016/s0140-6736(72)91310-4.
8
Liver involvement in polymyalgia rheumatica.风湿性多肌痛中的肝脏受累情况。
Scand J Rheumatol. 1976;5(4):197-204. doi: 10.3109/03009747609099905.

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