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风湿性多肌痛与抗线粒体抗体

Polymyalgia rheumatica and antimitochondrial antibodies.

作者信息

Sattar M A, Cawley M I, Hamblin T J, Robertson J C

出版信息

Ann Rheum Dis. 1984 Apr;43(2):264-6. doi: 10.1136/ard.43.2.264.

DOI:10.1136/ard.43.2.264
PMID:6712299
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1001480/
Abstract

Antimitochondrial antibodies (AMA) were detected in the sera of 11 of 36 patients with a clinical diagnosis of polymyalgia rheumatica (PMR) in whom comprehensive autoantibody screening had been performed. AMA did not correlate with biochemical changes of hepatic dysfunction, which are common in PMR, nor with parameters of musculoskeletal inflammation. Possible explanations are discussed.

摘要

在36例临床诊断为风湿性多肌痛(PMR)且已进行全面自身抗体筛查的患者中,11例患者血清中检测到抗线粒体抗体(AMA)。AMA与PMR中常见的肝功能障碍生化变化无关,也与肌肉骨骼炎症参数无关。文中讨论了可能的解释。

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引用本文的文献

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Antimitochondrial Antibodies and Primary Biliary Cholangitis in Patients with Polymyalgia Rheumatica/Giant Cell Arteritis.风湿性多肌痛/巨细胞动脉炎患者的抗线粒体抗体与原发性胆汁性胆管炎
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2
Liver involvement in polymyalgia rheumatica and giant cell arteritis.风湿性多肌痛和巨细胞动脉炎中的肝脏受累情况。
Reumatologia. 2020;58(6):444-445. doi: 10.5114/reum.2020.101580. Epub 2020 Dec 23.
3
High prevalence of anti-mitochondrial antibodies among patients with some well-defined connective tissue diseases.某些明确的结缔组织病患者中抗线粒体抗体的高患病率。
Clin Exp Immunol. 1986 Oct;66(1):68-76.
4
Antibodies to intermediate filaments in polymyalgia rheumatica and giant cell arteritis: a sequential study.风湿性多肌痛和巨细胞动脉炎中中间丝抗体的序贯研究。
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Liver scan abnormalities in polymyalgia rheumatica/giant cell arteritis.
Clin Rheumatol. 1991 Sep;10(3):294-7. doi: 10.1007/BF02208693.

本文引用的文献

1
Myalgic syndrome with constitutional effects; polymyalgia rheumatica.伴有全身影响的肌痛综合征;风湿性多肌痛
Ann Rheum Dis. 1957 Jun;16(2):230-7. doi: 10.1136/ard.16.2.230.
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Is mitochondrial antibody diagnostic of primary biliary cirrhosis?线粒体抗体能否诊断原发性胆汁性肝硬化?
Gut. 1981 Feb;22(2):136-40. doi: 10.1136/gut.22.2.136.
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Ultrastructural examination of the skeletal muscles in polymyalgia rheumatica.
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[Immunologic phenomena in liver diseases: significance of mitochondrial antibodies].[肝脏疾病中的免疫现象:线粒体抗体的意义]
Klin Wochenschr. 1969 Dec 15;47(24):1297-307. doi: 10.1007/BF01484292.
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Mitochondrial antibodies and subclinical liver disease.线粒体抗体与亚临床肝病
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Raised serum-alkaline-phosphatase levels in polymyalgia rheumatica.风湿性多肌痛患者血清碱性磷酸酶水平升高。
Lancet. 1972 Aug 12;2(7772):328. doi: 10.1016/s0140-6736(72)92932-7.
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Giant-cell arteritis and raised serum-alkaline-phosphatase levels.
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Liver involvement in polymyalgia rheumatica.风湿性多肌痛中的肝脏受累情况。
Scand J Rheumatol. 1976;5(4):197-204. doi: 10.3109/03009747609099905.
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Polymyalgia rheumatica and primary biliary cirrhosis.风湿性多肌痛和原发性胆汁性肝硬化。
Br Med J. 1978 Oct 21;2(6145):1128. doi: 10.1136/bmj.2.6145.1128.