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[红细胞光损伤与紫外线辐射强度之间的关系]

[Relation between erythrocyte photodamage and the intensity of ultraviolet radiation].

作者信息

Roshchupkin D I, Lordkipanidze A T

出版信息

Biofizika. 1984 Jan-Feb;29(1):155-6.

PMID:6713003
Abstract

Photoperoxidation of lipids (PPOL) in erythrocytes membranes and photohemolysis are essentially weakened with an increase of UV - irradiation intensity at constant irradiation dose. The initial part of the relationship between PPOL product concentration or rate of hemolysis and irradiation intensity is of a linear pattern. This is explained by the fact that the breakage of the chains of lipid free radical photooxidation on endogenous alpha-tocopherol is more effective than disproportionation of peroxide free radicals.

摘要

在恒定照射剂量下,随着紫外线照射强度的增加,红细胞膜中脂质的光氧化(PPOL)和光溶血作用基本减弱。PPOL产物浓度或溶血速率与照射强度之间关系的初始部分呈线性模式。这是因为内源性α-生育酚对脂质自由基光氧化链的断裂比过氧化物自由基的歧化更有效。

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