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[紫外线照射后雌二醇和生育酚对红细胞膜脂质过氧化的影响]

[Effect of estradiol and tocopherol on peroxidation of erythrocyte membrane lipids following ultraviolet irradiation].

作者信息

Denisov Iu P

出版信息

Farmakol Toksikol. 1978 Nov-Dec;41(6):697-701.

PMID:720582
Abstract

The effect of the antioxidants estradiol and tocopherol on the lipid photoperoxidation in the erythrocyte membranes of rats under UV-irradiation was investigated. Both agents are shown to inhibit the release of potassium ions and hemoglobin provoked by UV-rays, estradiol activity being higher as compared to that of tocopherol. High activity of estradiol is due to the fact that this antioxidant does not lose its antiradical properties when its molecules are exposed to UV-irradiation.

摘要

研究了抗氧化剂雌二醇和生育酚对紫外线照射下大鼠红细胞膜脂质光过氧化的影响。结果表明,这两种试剂均能抑制紫外线引发的钾离子和血红蛋白的释放,与生育酚相比,雌二醇的活性更高。雌二醇的高活性归因于这样一个事实,即当该抗氧化剂分子受到紫外线照射时,其不会丧失抗自由基特性。

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