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The direct enantiomeric determination of (-)- and (+)-propranolol in human serum by high-performance liquid chromatography on a chiral stationary phase.

作者信息

Wainer I W, Doyle T D, Donn K H, Powell J R

出版信息

J Chromatogr. 1984 Mar 9;306:405-11. doi: 10.1016/s0378-4347(00)80907-x.

DOI:10.1016/s0378-4347(00)80907-x
PMID:6715481
Abstract
摘要

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1
The direct enantiomeric determination of (-)- and (+)-propranolol in human serum by high-performance liquid chromatography on a chiral stationary phase.
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引用本文的文献

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Circadian changes in the pharmacokinetics and cardiovascular effects of oral propranolol in healthy subjects.健康受试者口服普萘洛尔的药代动力学和心血管效应的昼夜变化。
Eur J Clin Pharmacol. 1988;33(6):619-24. doi: 10.1007/BF00542498.
2
Enantiomeric resolution of drug compounds by liquid chromatography.通过液相色谱法拆分药物化合物的对映体
Pharm Res. 1987 Aug;4(4):285-92. doi: 10.1023/a:1016437018323.
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Measurement of underivatized propranolol enantiomers in serum using a cellulose-tris(3,5-dimethylphenylcarbamate) high-performance liquid chromatographic (HPLC) chiral stationary phase.
Pharm Res. 1988 Mar;5(3):187-9. doi: 10.1023/a:1015921124857.
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Clinical pharmacokinetic considerations in the elderly. An update.老年人的临床药代动力学考量。最新进展。
Clin Pharmacokinet. 1989 Oct;17(4):236-63. doi: 10.2165/00003088-198917040-00003.