Courtney K D, Andrews J E
J Environ Sci Health B. 1984 Feb;19(1):83-94. doi: 10.1080/03601238409372416.
HBB (hexabromobenzene) and HFB (hexafluorobenzene) were tested for their teratogenic potential in CD-1 mice. HBB and HFB were administered to pregnant mice from the 6th to the 16th day of gestation by gastric intubation. Neither HBB nor HFB were teratogenic or fetotoxic at doses up to 98.6 mg HBB/kg and 65.3 mg HFB/kg. No maternal toxicity was noted. HBB concentration in the fetuses indicated little, if any accumulation. No HFB was detected in the fetal or maternal tissues 24 hours after the last dose.
对六溴苯（HBB）和六氟苯（HFB）在CD-1小鼠中的致畸潜力进行了测试。在妊娠第6天至第16天，通过胃插管法给怀孕小鼠施用HBB和HFB。剂量高达98.6毫克HBB/千克和65.3毫克HFB/千克时，HBB和HFB均无致畸性或胚胎毒性。未观察到母体毒性。胎儿体内的HBB浓度表明几乎没有积累（如果有积累的话也极少）。末次给药24小时后，在胎儿或母体组织中未检测到HFB。
