Kung I T, Gibson J B, Bannatyne P M
Pathology. 1984 Jan;16(1):39-44. doi: 10.3109/00313028409067909.
Kimura's disease is a chronic inflammatory condition producing subcutaneous tumour-like nodules chiefly in the head and neck region. It is characterized histologically by lymphoid follicles, intense aggregations of eosinophils, vascular proliferation and fibrosis. Superficial lymph nodes and parotid glands are sometimes involved. The lesions may persist unchanged for years and new ones are apt to occur. Recurrences are also common. There are no systemic manifestations apart from peripheral blood eosinophilia. The lesion has been recognised as a distinct clinicopathological entity in the Far East for over 40 years. We describe 21 cases of Kimura's disease and discuss its relationship to angiolymphoid hyperplasia with eosinophilia. Although the pathogenesis and etiology of both these lesions are unknown we believe that there are sufficient significant clinical and pathological differences to justify their separation.
木村病是一种慢性炎症性疾病，主要在头颈部产生皮下肿瘤样结节。其组织学特征为淋巴滤泡、嗜酸性粒细胞密集聚集、血管增生和纤维化。浅表淋巴结和腮腺有时也会受累。病变可能多年保持不变，且容易出现新的病变。复发也很常见。除外周血嗜酸性粒细胞增多外，无全身表现。40多年来，该病变在远东地区被认为是一种独特的临床病理实体。我们描述了21例木村病病例，并讨论了其与嗜酸性粒细胞增多性血管淋巴样增生的关系。尽管这两种病变的发病机制和病因尚不清楚，但我们认为存在足够显著的临床和病理差异，足以证明将它们分开是合理的。
