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木村病罕见的腮腺内定位:一例报告。

Rare intraparotid gland localization of Kimura's disease: A case report.

作者信息

Majdi Trigui, Majd Werda, Moncef Sellami, Rania Kharrat, Ilheme Charfeddine, Werda Majd

机构信息

ENT - Head and Neck Department, Habib Bourguiba University Hospital, Sfax, Tunisia.

ENT Department, Habib Bourguiba University Hospital, Sfax, Tunisia.

出版信息

Int J Surg Case Rep. 2025 May;130:111280. doi: 10.1016/j.ijscr.2025.111280. Epub 2025 Apr 7.

Abstract

INTRODUCTION AND IMPORTANCE

Kimura's disease, a rare chronic inflammatory disorder of uncertain etiology, predominantly affects Asian males. Its occurrence in non-Asian individuals is uncommon, often leading to diagnostic delays. We present a North African case to underscore its global relevance.

CASE PRESENTATION

A 31-year-old male presented with a 6-year history of a firm, mobile parotid mass. MRI identified a nodular lesion in the superficial parotid lobe. Histopathology confirmed Kimura's disease. The patient underwent exofacial parotidectomy with no recurrence.

CLINICAL DISCUSSION

Kimura's disease must be distinguished from malignant or infectious parotid masses. Surgical excision is curative for localized disease; corticosteroids address systemic involvement. Renal complications (seen in 50 % of cases) require monitoring. Radiotherapy/immunosuppressants remain adjunctive.

CONCLUSION

This case emphasizes including Kimura's disease in differential diagnoses of parotid masses, regardless of ethnicity. Its diagnosis is based on histopathologic findings, and treatment should be individualized.

摘要

引言与重要性

木村病是一种病因不明的罕见慢性炎症性疾病,主要影响亚洲男性。在非亚洲个体中发病并不常见,常导致诊断延迟。我们报告一例来自北非的病例,以强调其在全球范围内的相关性。

病例介绍

一名31岁男性,有一个质地坚硬、可活动的腮腺肿块,病史长达6年。磁共振成像(MRI)显示腮腺浅叶有一个结节性病变。组织病理学确诊为木村病。患者接受了腮腺外切除术,无复发。

临床讨论

木村病必须与腮腺恶性或感染性肿块相鉴别。手术切除对局限性疾病有治愈作用;皮质类固醇可用于治疗全身受累情况。肾脏并发症(见于50%的病例)需要监测。放疗/免疫抑制剂仍作为辅助治疗。

结论

该病例强调,无论种族如何,在腮腺肿块的鉴别诊断中都应考虑木村病。其诊断基于组织病理学检查结果,治疗应个体化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7e3/12005856/c3b5c2caabc4/gr1.jpg

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