Bartness T J, Ruby N F, Wade G N
Physiol Behav. 1984 Jan;32(1):85-90. doi: 10.1016/0031-9384(84)90075-1.
High-fat diet-feeding increases body weight and adiposity in Syrian hamsters (Mesocricetus auratus), effects due in part to decreased energy expenditure. The effects of voluntary exercise- or cold exposure-induced increases in energy expenditure were examined in fat- or chow-fed, female Syrian hamsters. In Experiment 1, voluntary exercise (10 weeks) caused a moderate hyperphagia and actually increased body weight in both diet groups through increases in lean body mass. Carcass lipid was not affected by by exercise in chow-fed hamsters and only slightly reduced in fat-fed animals. In Experiment 2, chronic (8 weeks) cold exposure (5 degrees C) increased energy intake to the same extent in both dietary groups relative to the warm-exposed (23 degrees C) controls. High-fat diet-induced obesity was largely prevented by cold exposure. Cold exposure reduced lean body mass in chow-fed hamsters, but this carcass component was spared by fat-feeding. These results indicate that the increased metabolic demands of cold exposure were more effective in preventing this form of diet-induced obesity than those of voluntary exercise (80% and 17% reductions in carcass lipid, respectively). These results are discussed in terms of possible beneficial effects of eating a lipid-rich diet prior to winter.
高脂饮食会增加叙利亚仓鼠（金仓鼠）的体重和肥胖程度，部分原因是能量消耗减少。研究了在喂食高脂或普通饲料的雌性叙利亚仓鼠中，自愿运动或冷暴露引起的能量消耗增加的影响。在实验1中，自愿运动（10周）导致适度的食欲亢进，并且通过瘦体重增加，实际上使两个饮食组的体重都增加了。在喂食普通饲料的仓鼠中，运动对胴体脂质没有影响，而在喂食高脂饲料的动物中，胴体脂质仅略有减少。在实验2中，相对于温暖暴露（23摄氏度）的对照组，慢性（8周）冷暴露（5摄氏度）使两个饮食组的能量摄入增加程度相同。冷暴露在很大程度上预防了高脂饮食引起的肥胖。冷暴露使喂食普通饲料的仓鼠的瘦体重减少，但高脂喂养使这种胴体成分得以保留。这些结果表明，冷暴露增加的代谢需求在预防这种饮食诱导的肥胖方面比自愿运动更有效（胴体脂质分别减少80%和17%）。从冬季前食用富含脂质的饮食可能产生的有益影响方面对这些结果进行了讨论。
