Ambrosetto G, Riva R, Baruzzi A
Acta Neurol Scand. 1984 Mar;69(3):186-9. doi: 10.1111/j.1600-0404.1984.tb07799.x.
Two patients developed asterixis while they were taking carbamazepine at "therapeutic" levels. The only laboratory abnormality was slight hyperammonemia. It occurred with normal hepatic function as a dose-related effect. In fact, the blood ammonia level decreased and asterixis ceased when carbamazepine was stopped or reduced in dosage. The relationship between asterixis and hyperammonemia during carbamazepine therapy is discussed.
两名患者在服用“治疗剂量”的卡马西平时出现了扑翼样震颤。唯一的实验室异常是轻度高氨血症。它在肝功能正常的情况下作为一种剂量相关效应出现。事实上，当停用卡马西平或减少其剂量时，血氨水平下降且扑翼样震颤消失。本文讨论了卡马西平治疗期间扑翼样震颤与高氨血症之间的关系。
