Mok J Y, Simpson H
Arch Dis Child. 1984 Apr;59(4):306-9. doi: 10.1136/adc.59.4.306.
The clinical and respiratory function characteristics of 200 children 7 years after their admission to hospital with acute lower respiratory tract infection in infancy have been presented. Results were subsequently analysed according to disease category (bronchitis, bronchiolitis, or pneumonia) at initial presentation. Within each diagnostic category recurrent cough and wheeze, a tendency for colds 'to go to the chest', medication, absence from school, and family doctor consultations were significantly increased. Ventilatory function was diminished and bronchial reactivity increased when compared with matched controls. Studies of a different design are required to elucidate the mechanisms whereby symptoms are increased, ventilatory function impaired, and bronchial reactivity increased after severe lower respiratory infection in infancy.
本文介绍了200名婴儿期因急性下呼吸道感染入院7年后儿童的临床和呼吸功能特征。随后根据初次就诊时的疾病类别（支气管炎、细支气管炎或肺炎）对结果进行了分析。在每个诊断类别中，反复咳嗽和喘息、感冒“发展为胸部疾病”的倾向、用药情况、缺课情况以及家庭医生会诊次数均显著增加。与匹配的对照组相比，通气功能下降，支气管反应性增加。需要采用不同设计的研究来阐明婴儿期严重下呼吸道感染后症状增加、通气功能受损和支气管反应性增加的机制。
