Davies J M
Br J Ind Med. 1984 May;41(2):170-8. doi: 10.1136/oem.41.2.170.
Long term mortality was studied in a group of 57 chromate pigment workers who suffered clinical lead poisoning, mostly between 1930 and 1945. One death was attributed to lead poisoning and there were significant excesses of deaths from nephritis (observed/expected 3/0.24) and cerebrovascular disease (9/2.20), as well as non-significant excesses for respiratory diseases (7/3.59) and accidents and violence (3/1.13). The deaths from nephritis followed long spells of service exceeding 10 years. Poisoning appeared to have more adverse long term effects on older workers: 15 men aged 40 or over at the time of acute poisoning experienced generally high mortality, and 30 years later or by the end of 1981 only two survived instead of the seven expected. The risk of cerebrovascular disease appeared to be unrelated to duration of exposure and affected even men employed for under one year. Excluding the 57 lead poisoned men, other contemporary workers at the factories showed no excess mortality from cerebrovascular disease.
对一组57名铬酸盐颜料工人的长期死亡率进行了研究，这些工人大多在1930年至1945年间患临床铅中毒。有1例死亡归因于铅中毒，肾炎（观察到的/预期的为3/0.24）和脑血管疾病（9/2.20）的死亡人数显著超标，呼吸系统疾病（7/3.59）以及事故和暴力事件（3/1.13）的死亡人数超标但不显著。肾炎导致的死亡发生在超过10年的长期工作之后。中毒似乎对年长工人有更不利的长期影响：15名在急性中毒时年龄在40岁及以上的男性总体死亡率普遍较高，30年后或到1981年底，预期的7人仅2人存活。脑血管疾病的风险似乎与接触时间无关，甚至对工作不到一年的男性也有影响。排除这57名铅中毒男性后，工厂其他同时期的工人未出现脑血管疾病导致的超额死亡率。
