Becker L E, Armstrong D L, Chan F, Wood M M
Brain Res. 1984 Mar;315(1):117-24. doi: 10.1016/0165-3806(84)90083-x.
Using quantitative techniques on rapid Golgi impregnations, the dendrites from neurons of visual cortex from 14 infants ranging in age from 20 weeks gestation to 7 years were assessed. Neurons in layers 3 and 5 were separately evaluated. The total dendritic length for all dendritic branches reached a maximum of 2800 microns for layer 3 neurons and 3400 microns for layer 5 neurons. At or before 40 weeks gestation, the dendritic tree of layer 3 neurons had reached 35% of the maximum compared with 55% of the maximum for layer 5 neurons. Dendritic branching occurred earlier in layer 5 and growth continued to be more advanced than in layer 3. After 40 weeks gestation in these layers no new branch orders were added to basal dendrites but 3 branch orders were added to apical dendrites. The determination of normal values for dendritic length, number of orders, and number of branches during early development provides a foundation for comparison of dendritic maturation in children with a variety of neurologic disorders.
运用定量技术对快速高尔基染色标本进行研究，评估了14名年龄从妊娠20周至7岁婴儿视觉皮层神经元的树突。分别对第3层和第5层的神经元进行了评估。第3层神经元所有树突分支的总长度最长达到2800微米，第5层神经元为3400微米。在妊娠40周时或之前，第3层神经元的树突树达到最大值的35%，而第5层神经元为最大值的55%。第5层的树突分支出现得更早，并且其生长比第3层更超前。在这些层中，妊娠40周后，基底树突没有增加新的分支阶，但顶树突增加了3个分支阶。确定早期发育过程中树突长度、分支阶数和分支数量的正常值，为比较患有各种神经系统疾病儿童的树突成熟情况奠定了基础。
