Mascola L, Cable D C, Walsh P, Guinan M E
Clin Pediatr (Phila). 1984 Jul;23(7):400-3. doi: 10.1177/000992288402300708.
This report describes a case of probable herpes simplex virus (HSV) pneumonia in a neonate with no other localized signs of HSV infection. A 37-week-old infant became ill on the fourth day of life and died 6 days later of overwhelming pneumonia and ensuing complications. After the infant's death, viral cultures from the trachea, nasopharynx, and gastric aspirate grew herpes simplex virus. The mother had no history or signs of HSV infection at delivery. She developed a postpartum fever, and 8 days later herpetic lesions were noticed on the vulva and buttocks. The source of this infant's infection was most likely the maternal birth canal. Nosocomial acquisition could not be ruled out, but no history of HSV infection was found in either involved hospital personnel or in 38 infants defined to be at risk for nosocomial acquisition of the disease. Neonatal HSV can present as a rapidly progressive pneumonia without other clues to etiology.
本报告描述了一例新生儿单纯疱疹病毒（HSV）肺炎病例，该新生儿无其他HSV感染的局部体征。一名37周龄的婴儿在出生后第4天发病，6天后死于严重肺炎及随之而来的并发症。婴儿死亡后，气管、鼻咽部和胃吸出物的病毒培养物中培养出单纯疱疹病毒。母亲在分娩时无HSV感染病史或体征。她产后发热，8天后在外阴和臀部发现疱疹性损害。该婴儿感染的来源很可能是母亲的产道。不能排除医院感染，但在相关医院工作人员或38名被确定有医院感染该病风险的婴儿中均未发现HSV感染病史。新生儿HSV感染可表现为快速进展的肺炎，而无其他病因线索。
