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肿瘤细胞中的抗氧化剂：II. 从分化的小鼠神经母细胞瘤细胞中分离出一种酚类抗氧化剂并对其进行部分表征。

Antioxidants in neoplastic cells: II. Isolation and partial characterization of a phenolic antioxidant from differentiated mouse neuroblastoma cells.

作者信息

Arneson R M

出版信息

Lipids. 1978 Jun;13(6):391-5. doi: 10.1007/BF02533707.

DOI:10.1007/BF02533707
PMID:672479
Abstract

The generation of an antioxidant has been shown to be associated with the dramatic increase in resistance to lipid peroxidation which occurs during the differentiation of mouse neuroblastoma cells in culture. The antioxidant has been isolated from the neuroblastoma neutral lipid fraction and partially characterized by means of low-resolution and high-resolution mass spectrometry and other lines of evidence. All presently available information suggests that this antioxidant is a highly aromatic, monosubstituted phenol having the molecular formula C19H14O2.

摘要

业已表明，抗氧化剂的生成与在培养的小鼠神经母细胞瘤细胞分化过程中出现的对脂质过氧化抗性的显著增加有关。该抗氧化剂已从神经母细胞瘤中性脂质部分中分离出来，并通过低分辨率和高分辨率质谱法及其他证据进行了部分表征。目前所有可得信息表明，这种抗氧化剂是一种分子式为C19H14O2的高度芳香化的单取代苯酚。

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引用本文的文献

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Antioxidants in neoplastic cells: I. Changes in the antioxidative capacity of mouse neuroblastoma cells measured by a single-phase assay.肿瘤细胞中的抗氧化剂：I. 通过单相测定法测量小鼠神经母细胞瘤细胞抗氧化能力的变化。
Lipids. 1978 Jun;13(6):383-90. doi: 10.1007/BF02533706.
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Lipids. 1978 Jun;13(6):383-90. doi: 10.1007/BF02533706.
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