Schreiber M M, Moon T E, Bozzo P D
J Am Acad Dermatol. 1984 May;10(5 Pt 1):755-9. doi: 10.1016/s0190-9622(84)70090-9.
A retrospective study of 226 cases of cutaneous malignant melanoma (CMM) was done to determine if patients with CMM showed evidence of chronic solar ultraviolet radiation damage, i.e., a past history of actinic keratosis (AK), basal cell carcinoma (BCC), squamous cell carcinoma (SCC) anywhere on the patient's skin, and solar elastosis (SE) at the site of a CMM. This statistical analysis consisted of 119 clinical records and 158 pathology slides after all cases of lentigo CMM were deleted. CMM showed no statistical correlation with AK, BCC, SCC, or SE. This supports the idea that it is not the chronic solar-ultraviolet radiation exposure that causes CMM.
对226例皮肤恶性黑色素瘤（CMM）患者进行了一项回顾性研究，以确定CMM患者是否有慢性日光紫外线辐射损伤的证据，即光化性角化病（AK）、基底细胞癌（BCC）、鳞状细胞癌（SCC）的既往病史，这些病变出现在患者皮肤的任何部位，以及CMM部位的日光性弹力组织变性（SE）。在删除所有雀斑样痣型CMM病例后，该统计分析包括119份临床记录和158张病理切片。CMM与AK、BCC、SCC或SE之间无统计学相关性。这支持了不是慢性日光紫外线辐射暴露导致CMM的观点。
